Lipid Peroxide and Disease

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Antioxidant Enzymes and Acute Phase Proteins Correlate with Marker of Lipid Peroxide in Adult Nigerian Sickle Cell Disease Patients

Objective(s) Sickle cell disease is a genetic disorder characterized by chronic haemolytic anaemia. Haemoglobin S containing red blood cells may be susceptible to oxidative stress due to imbalance between production of reactive oxygen species and the countering effect of the various antioxidants present in the body. Materials and Methods We evaluated some antioxidant enzymes which include gl...

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Lipid Peroxide Formation in Microsomes

or ferricyanide were not able to replace ascorbate and induce lipid peroxide formation. 2. The rate of ascorbate-induced peroxidation is optimum at pH 6-0 whereas the rate of the NADPH system is optimum at pH7-0. Both systems require phosphate for maximum activity. 3. Lipid peroxide formation occurs at the maximum specific rate in very dilute microsome suspensions (0-15mg. of protein/ ml.). 4. ...

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Superoxide dismutase activity, lipid peroxide production

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antioxidant enzymes and acute phase proteins correlate with marker of lipid peroxide in adult nigerian sickle cell disease patients

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Studies of paroxysmal nocturnal hemoglobinuria erythrocytes: increased lysis and lipid peroxide formation by hydrogen peroxide.

When paroxysmal nocturnal hemoglobinuria (PNH) erythrocytes were exposed to H(2)O(2) they lysed excessively and formed greater than normal quantities of lipid peroxides when compared to red cells of normal subjects and patients with most types of hematologic disease. It was also shown that lytic sensitivity to acidified serum was related to the enhanced lytic sensitivity to H(2)O(2). If the lip...

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ژورنال

عنوان ژورنال: Journal of Japan Oil Chemists' Society

سال: 1988

ISSN: 1884-2003

DOI: 10.5650/jos1956.37.872